Professor Gottfried Otting  

Professor Gottfried Otting

Administering Organisation    

Discipline Area        

The Australian National University

Biological Sciences and Biotechnology

Fellowship project summary

Proteins in motion—new tools for biotechnology (FL170100019)

This project aims to assess the function of proteins by monitoring their motions using new nuclear magnetic resonance (NMR) spectroscopy techniques. As snapshots of 3D protein structures have been determined by crystallography, the new tools are designed to analyse functionally important motions in solution. A facility for ultrafast (> 100 kHz) magic angle spinning NMR spectroscopy of proteins in the semi-solid state will bring cutting-edge know-how to Australia and allow the interrogation of 3D structure and dynamics in selected protein regions. The expected outcomes of the project will have immediate benefits for the rational engineering of biocatalysts and in the design of lead compounds in drug development.

Australian Research Council funding: $2,606,250

About Professor Otting

Professor Gottfried Otting is a Professor within the Research School of Chemistry, where he leads   Biomolecular nuclear magnetic resonance (NMR) spectroscopy. Professor Otting moved to Australia in 2002 to undertake a five-year ARC Federation Fellowship at The Australian National University. Professor Otting’s research centres on the development of NMR methods for drug development. He is a leader in the development of NMR techniques. He was awarded the 1996 Wallmarkska Prize of the Royal Swedish Academy of Sciences, the 2010 Alexander von Humboldt Research Award, the 2013 Medal of the Australian and New Zealand Society of Magnetic Resonance and is a foreign member of the Latvian Academy of Sciences.

Find out more about Professor Otting and his research by visiting his profile page on The Australian National University website.

For further information about this funding scheme, please visit the Australian Laureate Fellowships scheme page on the ARC website.

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