Scientists 3D print human pluripotent stem cells—26 July 2017

Researchers at the ARC Centre of Excellence for Electromaterials Science (ACES) at the University of Wollongong have discovered a way to print human induced pluripotent stem cells (iPSCs) using a custom developed bioink.

ACES stem cell expert, Associate Professor Jeremy Crook, said iPSCs can be generated from cells of any living person, and be 3D printed to incorporate properties of the natural cell environment.

“This flexible 3D tissue engineering technology enables iPSCs generated from an individual’s own body to divide after printing and differentiate in a way that will allow us to form and replace any tissue type of the body,” he said. “By developing this further we will be able to generate healthy and diseased tissues for research, identifying better drugs for medicine and replacing or repairing damaged tissues or organs due to injury or disease.”

The team has already begun work to advance tissues further for use in medical research, regenerative medicine and personalised medicine. Using tissues developed from clinically-compliant bioinks with iPSCs will allow therapeutic transplants with a reduced risk of immune rejection.

Media issued by the University of Wollongong.

 

Image: Left: Delicate neurones created by 3D printing; and, right: iPSC-laden bioink formed in scaffolds containing stem cells.
Image credit: Images: Gu et al/Advanced Healthcare.

Original Published Date: 
Wednesday, July 26, 2017