An example super resolution image using the new technique.
Original Published Date: 
Monday, August 19, 2019

Full article issued by The ARC Centre of Excellence for Nanoscale BioPhotonics.

Australian researchers from the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) have reported in Nature Communications a simple way to bypass the limitations in optical microscopes, which will allow them to observe how life works at a nanoscale level, with a simple system that can be incorporated into existing tools.

Standard optical microscopes can image cells and bacteria but not their nanoscale features which are blurred by a physical effect called diffraction. Optical microscopes have evolved over the last two decades to overcome this diffraction limit; however, these so-called super-resolution techniques typically require expensive and elaborated instrumentation or imaging procedures.

Lead CNBP authors, including Discovery Early Career Research Award (DECRA) recipient, Dr Martin Ploschner, and Dr Denitza Denkova, say that it was by working closely with biologists at the ARC Centre of Excellence that inspired them to look for a solution to transform super-resolution from a complex and expensive imaging method into an everyday bio-imaging technique.

Photo credit: 

An example super resolution image using the new technique. Credit: CNBP.