an image from the project's 3D brain viewer
Original Published Date: 
Tuesday, January 21, 2020

Full article issued by The ARC Centre of Excellence for Integrative Brain Function.

Researchers at The ARC Centre of Excellence for Integrative Brain Function (Brain Function CoE) and the US National Institutes of Health, have produced the first complete high-resolution 3D map of 'white matter'—the internal tissue of the brain that contains many long connective nerve fibres—in marmosets.

The researchers combined new high resolution imaging data with information from the Brain Function CoE’s Marmoset Brain Connectivity Atlas, which maps the connections between different areas of the cortex—the part of the brain that covers the white matter.

The resulting map of white matter organization reveals a structure that is even more complex than previously suspected. The unprecedented resolution of the map also uncovered features that hadn’t been seen before and allowed the researchers to correctly identify features that had been misidentified in previous maps.

The new brain map provides insights into brain connectivity in humans, and will give researchers a better understanding of how its connectivity could help to explain symptoms in diseases such as depression and schizophrenia.

Photo credit: 

An image from the project team's 3D marmoset brain viewer. Credit: WinterRollx (Zhongmian Wang) and Cirong Liu, MarmosetBrainMapping.org.